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Enterprise grade, here to stay

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Mission

Built for scale

Cleaner, safer, more efficient chemical manufacture. A spinout from the University of Oxford, commercialising a novel biotechnology. Our ‘slot in’ technologies allow you to replace your heavy metal catalyst for hydrogenation reactions, or decarbonise existing redox biocatalysis processes all whilst operating within existing flow hydrogenation reactors.

From HydRegen's home page meta description and copy.

Backers, partners and programmes named on HydRegen's site
Genoa VenturesClean Growth FundFirst Imagine! VenturesUniversity of OxfordInnovate UKRoyal Society of Chemistry
Traction

What HydRegen has published

“HydRegen is led by an experienced, multidisciplinary team spanning science, scale-up, operations and commercialisation. Together, we have the expertise to take HydRegen’s biotech platforms from breakthrough technology to successful industrial adoption.”

Source: https://hydregenoxford.com/leadership

“➡ 3 x CO2 savings compared to traditional metal catalysed hydrogenations ➡ benchmarking for paracetamol production ➡ clean and efficient chemistry ➡ >£2.6m clean tech funding ➡ supported by University of Oxford , Oxford University Innovation and Prof Kylie Vincent”

Source: https://hydregenoxford.com/news/video

“HydRegen, the revolutionary bioscience company, is excited to announce the appointment of Matthew Hodges as Commercial and Operations Lead, directing the commercial strategy and assisting in the development of its lead product. Matt brings a strong background in building businesses for fundraising, winning public grant applications and creating successful partnerships in both commercial and scientific areas.”

Source: https://hydregenoxford.com/news/matt-hodges

“🚀 We are now looking to raise £8m, focusing on accelerating our growth, increasing joint-development capabilities and therefore fast-tracking licensing and revenue generation via commercial manufacturing.”

Source: https://hydregenoxford.com/news/a-year-of-success

“We were delighted to win a place on the UK trade mission to San Francisco, led by Innovate UK Business Growth, which centered on attending SynBioBeta. This was an excellent opportunity to meet other leading UK companies in the sector as well as US-based partners and investors.”

Source: https://hydregenoxford.com/news/a-year-of-success

“HydRegen, the Oxford-based biotechnology company enabling sustainable chemical manufacturing, has secured a £2.6 million investment as part of its latest fundraise, led by Clean Growth Fund , the UK clean-tech venture capital fund.”

Source: https://hydregenoxford.com/news/cgfinvestmentraise

“In March 2022, the company received £385,000 in funding from the UK Innovation & Science Seed Fund (UKI2S), alongside private investors, to work in collaboration with pharmaceutical and fine chemical companies wanting to reduce their costs and environmental impact.”

Source: https://hydregenoxford.com/news/cgfinvestmentraise

“Conference Participation : Invited to speak at numerous technical conferences and presented posters and flash talks.”

Source: https://hydregenoxford.com/news/chemistry2024review

Roadmap

Where it is heading

“Not only does this make it easier for us to scale, but it makes our technology transfer to partners and customers faster.”

Source: https://hydregenoxford.com

“We have a variety of commercial frameworks to meet end-user needs, recognizing different requirements at different stages of chemical manufacturing, from hit identification, through to scale up.”

Source: https://hydregenoxford.com

“In his new role, Pierre will work across HydRegen’s chemistry and engineering teams to help de-risk the company’s lead processes and advance them towards its manufacturing goals. His work will support the translation of strong laboratory results into robust and commercially relevant processes.”

Source: https://hydregenoxford.com/news

“As we work at increasingly higher Technology Readiness Levels (TRL 7+), we welcome Bethan and Stephen – whose combined experience bridges biocatalysis, continuous flow, process scale-up and industrial innovation to reduce our time to tech transfer and pilot scale manufacturing, accelerating commercial partnership timelines from 6-12 months to as little as 3-6 months.”

Source: https://hydregenoxford.com/news

“As the chemical manufacturing industry faces the dual pressures of sustainability and rising cost competition, it’s clear that next-generation technologies cannot rely on a “green premium” to succeed. While these emerging solutions offer significant benefits including reducing environmental impact, improving safety and fostering market growth, the challenges of implementation and cost must be carefully considered.”

Source: https://hydregenoxford.com/news

“Decarbonise biocatalysis: We believe that improving implementation of redox biocatalysis will ultimately speed up a switch to bio-based feedstocks, building circular and bio-based economies.”

Source: https://hydregenoxford.com/technology

Investors and press

In the news

Press

News

In his new role, Pierre will work across HydRegen’s chemistry and engineering teams to help de-risk the company’s lead processes and advance them towa

Press

Spinout spotlight

➡ 3 x CO2 savings compared to traditional metal catalysed hydrogenations ➡ benchmarking for paracetamol production ➡ clean and efficient chemistry ➡ >

Press

Meet Jack - our newest team member

We asked Jack to introduce himself and tell us about why he chose to study Chemistry, what brought him to HydRegen and what he’s learnt in his first m

Press

HydRegen appoint Matthew Hodges to evolve its lead catalyst technology product

HydRegen, the revolutionary bioscience company, is excited to announce the appointment of Matthew Hodges as Commercial and Operations Lead, directing

Press

HydRegen appoint Joe de Sousa as a Non-Executive Director

HydRegen, the revolutionary bioscience company, is pleased to announce the appointment of Joe de Sousa as Non-Executive Director. With a background in

Press

HydRegen appoint Miguel Ramirez to scale up their proprietary enzyme platform

HydRegen, the revolutionary bioscience company, have appointed Miguel Ramirez Hernandez as Head of Molecular Biology and Enzyme Production. Miguel wil

Press

Asynt Write-up

Every good start-up relies on high-quality resources, and it can’t be underestimated how first-rate equipment is aiding our research and development a

Press

JRSI and HydRegen: Making Green Hydrogenation A Reality

Huddersfield, United Kingdom - 11 June 2025 James Robinson Speciality Ingredients (JRSI) and HydRegen today announced a strategic collaboration to imp

Press

A year of success

🌱 HydRegen is a biotech company delivering cleaner, safer and more economical chemical manufacturing strategies.

Press

HydRegen successfully completes tech transfer to Almac Sciences as part of the j

HydRegen, the revolutionary bioscience company, completes first scale up demonstration of the joint HydRegen-Almac Sciences bio-manufacturing route to

Press

HYDREGEN RAISE £2.6M

Revolutionary Oxford biotechnology company pursues a huge growth opportunity to decarbonise the global chemical manufacturing and pharmaceutical indus

Press

Chemistry Team: A Year of Innovation and Industrial Progress

As we wrap up another year of groundbreaking research and development, we are thrilled to share the remarkable achievements of our Chemistry Team. Thi

Press

HydRegen

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Press

HydRegen’s 2025 Outlook

We are proud to initiate two groundbreaking joint development projects targeting the sustainable production of widely used consumer products. These co

Press

How we work with Pharma

The pharmaceuticals landscape is changing, in a positive way, and there is a growing appetite from both business and regulators for new technology and

Press

Webinar with ThalesNano

An invitation by ThalesNano to give a webinar was too good an opportunity to miss! Ever since we started thinking about working in continuous flow (ba

Press

HydRegen formal spinout

The HydRegen technology is grounded in 10 years of academic research and formally spanout of the Department of Chemistry, University of Oxford in Marc

Press

Write up by Advanced Oxford

We are delighted to have been highlighted as a Case Study by Advanced Oxford as part of the 'Green Recovery’ series.

Press

Making an impact at NextGenBiocat

Following their attendance at the recent NextGenBiocat symposium, HydRegen’s Chief Scientific Officer, Sarah Cleary, and Product Development Specialis

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Our Summer 2024 process progress

HydRegen’s industrial biotechnology platforms deliver sustainable, safe and cost-efficient chemical processes. Partnerships with major chemicals compa

Press

Supporting the scientists of future generations

HydRegen is passionate about finding and supporting both new and developed scientists who are committed to reducing the environmental impact of chemic

Press

From Harsh to Harmonious: The Shift in Chemical Processing

The chemicals sector is critical to nearly all manufacturing industries, converting raw materials like oil, natural gas, and minerals into essential c

Press

Autoclave Systems for Scalable and Efficient Hydrogenation

Hydrogenation, a fundamental chemical process with broad applications across petrochemicals, pharmaceuticals, and food production has traditionally re

Press

The Growth Strategy Series: A Closer Look at Yinqi’s Journey

At the core of HydRegen's mission to make chemical manufacturing safer and more sustainable lies a team of exceptional scientists dedicated to pushing

Press

Investing in Green Chemistry: Why BioTech is a Big Opportunity

Crucial to the global economy, the chemical industry underpins sectors from pharmaceuticals, agriculture to consumer goods and has one of the most com

Press

Sustainable Chemical Manufacturing: The Scale of the Challenge

As catastrophic climatic events become increasingly common and the world races toward the 1.5°C threshold outlined in the Paris Agreement, global indu

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Chemistry Biology Interface Horizon Prize, Royal Society of Chemistry

Reproduced from: Biocatalytic Nitro Hydrogenations team , Royal Society of Chemistry

Press

HydRegen Wins ‘Golden Ticket’ Programme for Planetary Health Innovations

Originally posted: University of Oxford Spin-Out Named Winner of ‘Golden Ticket’ Programme for Planetary Health Innovations - Pioneer Group (thepionee

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The Growth Strategy Series: A Chemist's Journey from Academia to a Startup

Following the introduction of Yinqi and her expertise in biocatalysis, we now turn to synthetic organic chemist, Becky .

Press

Embracing the Start-Up Experience: Alex's Journey from Undergrad to HydRegen

In today's competitive job market, early-stage undergraduates often gravitate toward established corporate giants, drawn in by their prestigious names

Press

HydRegen appoint John Boyle as a Scientist specialising in Organic Chemistry

HydRegen , the revolutionary bioscience company, is pleased to announce the appointment of John Boyle as a Scientist of Organic Chemistry. With more t

Press

HydRegen appoint Giovanni Davide Barone as a specialist in Molecular Biology

HydRegen, the revolutionary bioscience company, is proud to announce the appointment of Giovanni Davide Barone as Molecular Biology Specialist, to exp

Press

HydRegen Welcomes Kevin Matthews as Chair to Drive the Next Chapter of Growth

With over two decades of leadership in the global chemical industry, Kevin combines a deep understanding of the sector with proven experience in scali

Press

HydRegen Strengthens Capability with Appointment of Analytical and DSP Chemist

Oxford, UK – HydRegen is pleased to announce the appointment of Kat Usachova as Analytical and DSP Chemist, further strengthening the company's capabi

Press

Cultivating Success: HydRegen’s Leadership Journey Towards Commercial Excellence

From the outset of our partnership with HydRegen in June 2023, we have witnessed exceptional progress across all fronts, aligning with the leadership

Press

HydRegen appoint Piera De Santis as a Scientist specialising in Molecular Biolog

HydRegen, the revolutionary bioscience company, is pleased to announce the appointment of Piera De Santis as a Scientist of Molecular Biology. Followi

Press

HydRegen appoint Dr Willem Breukelaar as a Scientist specialising in Biocatalysi

HydRegen, the revolutionary bioscience company, is pleased to announce the appointment of Dr Willem Breukelaar as a Scientist and specialist in biocat

Press

Synthetic biology expertise will unlock new opportunities for scaling HydRegen t

Oxford, UK – HydRegen is pleased to welcome Mark Eldridge to the team as Synthetic Biologist, strengthening the company’s biological capabilities as i

Press

HydRegen Strengthens Process Development Capability with Appointment of Pierre M

HydRegen is pleased to welcome Pierre Moreau to the team as Process Engineer, Chemistry , strengthening the company’s process development and scale-up

Press

Heavy Metal Detox in Hydrogenation: How Bio-Based Enzymes are Driving a Sustaina

The future of industrial catalysis lies in bio-based solutions, and the time to invest in that future is now.

Press

From Global to Local

In recent decades, globalisation enabled the chemical manufacturing industry to outsource production to regions with lower labour costs, abundant raw